News

Immunosuppressive Tacrolimus Found Safe, Effective for Lupus Nephritis

The immunosuppressive agent tacrolimus, used in combination with other immunosuppressants, was deemed safe and effective for treatment of lupus nephritis, a serious complication of systemic lupus erythematosus (SLE), a new study shows. The study, “Efficacy and safety of tacrolimus in induction therapy of patients with lupus nephritis,” was published…

U.S. Patent Issued for Lupus Nephritis Treatment Protocol with Voclosporin

The U.S. Patent and Trademark Office (USPTO) is issuing a new patent to Aurinia Pharmaceuticals covering a method of use and dosing protocol of the immunosuppressant voclosporin in patients with lupus nephritis. The patent (No. 15/835,219), titled “Protocol for Treatment of Lupus Nephritis” covers an individualized treatment protocol where…

Lupus Therapeutics, Takeda Launch Phase 1 Trial of TAK-079 for Moderate to Severe SLE

The Lupus Research Alliance and its affiliate, Lupus Therapeutics, have partnered with Takeda Pharmaceutical to conduct a Phase 1 clinical trial testing Takeda’s investigational antibody TAK-079 for the treatment of systemic lupus erythematosus (SLE) patients. The trial (NCT03724916), which will include approximately 24 participants across the U.S., is for patients with…

Physical Fitness Linked with Better Quality of Life in Women with SLE

Physical fitness, particularly muscle strength and cardiorespiratory fitness, are associated with better quality of life scores in women with systemic lupus erythematosus (SLE), a study reports. The study, “Association of physical fitness components and health-related quality of life in women with systemic lupus erythematosus with mild disease activity,” was…