Posts by: Jose Marques Lopes, PhD

News

A low dose of the immunosuppressant leflunomide is as safe and effective as the standard of care cyclophosphamide for induction treatment of patients with lupus nephritis, according to a Phase 2/3 trial ... Read more

December 5, 2018

Evobrutinib’s Effects on Macrophages Could Be Beneficial for SLE Treatment, Study Suggests

News

The investigational compound evobrutinib acts on the immune system by promoting anti-inflammatory behavior of macrophages — immune cells that engulf and digest pathogens — and the death of pro-inflammatory ... Read more

November 30, 2018

Hydroxychloroquine Use Lowers Risk for Atrial Fibrillation in SLE Patients, Study Reports

News

Systemic lupus erythematosus (SLE) patients using hydroxychloroquine have a markedly lower risk of a type of abnormal heart rhythm called atrial fibrillation than those not being treated with the therapy, ... Read more

November 21, 2018

Benlysta Maintenance Does Not Change Kidney Function of Lupus Nephritis Patients, Phase 2 Trial Shows

News

Using Benlysta (belimumab) as a maintenance therapy after Rituxan (rituximab) leads to similar kidney function in patients with lupus nephritis compared with Rituxan alone, according to a Phase 2 clinical trial. The research, ... Read more

October 26, 2018

Ustekinumab Provides Sustained Decrease of SLE Disease Activity, Phase 2 Trial Shows

News

One year of treatment with ustekinumab led to sustained reductions in disease activity in systemic lupus erythematosus (SLE) patients, according to a Phase 2 trial. These benefits were also observed ... Read more

October 24, 2018October 24, 2018

Corticosteroids and Hydroxychloriquine Top Medications Used by SLE, Lupus Nephritis Patients, Study Reports

News

Corticosteroids and hydroxychloroquine are the most common medications used by patients with systemic lupus erythematosus (SLE) or lupus nephritis (LN), according to a real-world study, which also found very ... Read more

September 28, 2018

High SLE Disease Activity Over Time Warrants New Treatments, Study Asserts

News

The activity of systemic lupus erythematosus (SLE) is persistently high in a large proportion of patients, despite high rates of steroids and immunosuppressants use, according to a five-year study. The ... Read more

September 21, 2018

Pneumonia in SLE Associated with Adverse Prognosis, Study Reports

News

Patients with systemic lupus erythematosus (SLE) who develop pneumonia have a high risk of adverse prognosis, according to a new study. The findings also revealed that common scales of ... Read more

August 31, 2018August 31, 2018

Regen BioPharma Eyes Molecules Targeting Immune Protein NR2F6 as Lupus Therapy

News

A series of recently identified small molecules targeting a protein called NR2F6 could lead to new treatments for autoimmune diseases such as lupus, according to Regen BioPharma. NR2F6 is ... Read more

August 10, 2018August 10, 2018

Virgin Olive Oil May Help Reduce SLE Activity, Mouse Study Suggests

News

Virgin olive oil, especially its phenol components, showed anti-inflammatory properties in mice with systemic lupus erythematosus (SLE) and in human immune cells, according to a new Spanish study. The findings ... Read more

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Posts by: Jose Marques Lopes, PhD

Jose Marques Lopes, PhD

Low-dose Leflunomide Effective Induction Therapy for Lupus Nephritis, Phase 2/3 Trial Finds

Evobrutinib’s Effects on Macrophages Could Be Beneficial for SLE Treatment, Study Suggests

Hydroxychloroquine Use Lowers Risk for Atrial Fibrillation in SLE Patients, Study Reports

Benlysta Maintenance Does Not Change Kidney Function of Lupus Nephritis Patients, Phase 2 Trial Shows

Ustekinumab Provides Sustained Decrease of SLE Disease Activity, Phase 2 Trial Shows

Corticosteroids and Hydroxychloriquine Top Medications Used by SLE, Lupus Nephritis Patients, Study Reports

High SLE Disease Activity Over Time Warrants New Treatments, Study Asserts

Pneumonia in SLE Associated with Adverse Prognosis, Study Reports

Regen BioPharma Eyes Molecules Targeting Immune Protein NR2F6 as Lupus Therapy

Virgin Olive Oil May Help Reduce SLE Activity, Mouse Study Suggests

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