Posts by: Jose Marques Lopes, PhD

News

Rituxan (rituximab) could be a valid alternative to standard of care in systemic lupus erythematosus (SLE) patients with neurological and psychiatric manifestations, a new Italian case report shows. The research, “Severe ... Read more

October 4, 2017October 12, 2017

Montreal Test Seen as Most Effective at Measuring Cognitive Problems in Lupus

News

Cognitive impairment is highly prevalent in patients with systemic lupus erythematosus (SLE), a study from Canada finds. The research also addressed the validity of different screening tools for this ... Read more

August 29, 2017August 29, 2017

Alterations in White Blood Cell Levels in Lupus May Offer Clue to Underlying Mechanisms, Study Suggests

News

Levels of distinct immune cells, including certain monocyte subsets, are altered in systemic lupus erythematosus (SLE) patients, research from China indicates. The new study, “Upregulation of CD16- monocyte subsets ... Read more

August 24, 2017August 24, 2017

Immune Response Regulator Interferon-Gamma Is Associated with Cerebral Atrophy in Lupus, Study Suggests

News

Interferon-gamma, an endogenous regulator of immune responses, is associated with reduced cerebral volume in lupus patients, a new Brazilian study shows. The study, “Interferon-γ Is Associated with Cerebral Atrophy ... Read more

August 22, 2017

Damage Outside Blood-Cleaning Areas of Kidneys Can Predict End-stage Disease, Study Indicates

News

Damage to small tubes in the kidneys and the tissue that surrounds them is a strong predictor that lupus nephritis patients will develop an end-stage renal disease, a New York ... Read more

August 17, 2017

European Initiative Issues New Recommendations for Diagnosis, Treatment of Pediatric SLE

News

A European initiative called SHARE has issued new international guidelines for the diagnosis, management, and treatment of childhood-onset systemic lupus erythematosus (cSLE). The recommendations are expected to support uniform, ... Read more

July 11, 2017July 11, 2017

Anemia and Low Lymphocyte Numbers Are Most Common Blood Disorders in Lupus Patients, Study Finds

News

Low levels of red blood cells (anemia) and lymphocytes, a type of white blood cell, are the most frequent hematological disorders in patients with systemic lupus erythematosus (SLE), according to ... Read more

April 3, 2017April 3, 2017

Pfizer’s Antibody Against IL-6 Shows Promise as Treatment for Lupus in Phase 2 Trial

News

Results from the Phase 2 BUTTERFLY trial conducted by Pfizer suggest that an antibody against the pro-inflammatory cytokine interleukin-6 (IL-6) may be a promising treatment for systemic lupus erythematosus (SLE). The study, ... Read more

March 27, 2017March 27, 2017

Scientists Find Links Between Interleukin 17A and Inflammation, Organ Protection in SLE Patients

News

The cytokine interleukin 17A (IL-17A), while playing a role in inflammation, may also serve a protective purpose in systemic lupus erythematosus (SLE) patients, new research shows. The study, “IL-17A levels ... Read more

March 17, 2017March 17, 2017

Chinese Study Links High Autoantibody Levels Against PD-1 to Lupus Disease Activity

News

Patients with new-onset lupus erythematosus (SLE) have high levels of autoantibodies against programmed cell death protein 1 (PD-1), an immune response co-inhibitor, new research from China shows. The study, ... Read more