Discussion
Approved Treatments
for Lupus
Benlysta
Benlysta (belimumab) is an approved add-on therapy for people with active SLE and lupus nephritis. It is given as an into-the-vein infusion or under-the-skin injection. It works by blocking a protein that helps B-cells, immune cells involved in lupus, survive and become active.
Gazyva
Gazyva (obinutuzumab) is approved add-on therapy for adults with active lupus nephritis who are taking receiving therapies. It is administered via infusions into the bloodstream. It works by targeting CD20, a protein on B-cells, to reduce these immune cells and help control inflammation in the kidneys.
Lupkynis
Lupkynis (voclosporin) is an oral therapy approved for adults with active lupus nephritis. Taken as capsules alongside other immunosuppressive medications, it helps control the immune activity that causes kidney inflammation and damage while also protecting the kidneys from further permanent damage.
Saphnelo
Saphnelo (anifrolumab-fnia) is approved add-on therapy for adults with moderate to severe SLE. It is administered via an into-the-vein infusion or under-the-skin injection. It works by blocking the activity of interferons, immune proteins that contribute to inflammation in lupus.