Author Archives: Marisa Wexler, MS

Immune Regulator miRNA-142 Could Advance Cancer, Autoimmune Disease Research

A new study has identified a critical regulator of immunity, called microRNA-142, which could have significant implications for understanding or even treating autoimmune diseases and cancer. The study, “microRNA-142-mediated repression of phosphodiesterase 3B critically regulates peripheral immune tolerance,” was published in The Journal of Clinical Investigation. The…

Combined Immunosuppressive Treatment Safe, More Effective for Treating Lupus Nephritis, Study Finds

Adding an oral immunosuppressive agent and hydroxychloroquine to routine intravenous cyclophosphamide significantly increases response rates among patients with lupus nephritis without increasing the rate of severe adverse events, a randomized study found. The study, “Combined immunosuppressive treatment (CIST) in lupus nephritis: a multicenter, randomized controlled study,” was published…