Elevated blood levels of a marker called galectin-9 may help identify people with systemic lupus erythematous lupus (SLE) who have more active disease and organ damage, a study suggests. The study “Galectin-9 as a biomarker for disease activity in systemic lupus erythematosus” was published in the journal…
Platelet-bound C4d (PC4d), one of Exagen‘s patented biomarkers, may be used along with other available biomarkers to estimate the risk of thrombosis — the formation of blood clots — among people with systemic lupus erythematosus (SLE), a study shows. The study, “Platelet-bound C4d, low C3…
High levels of a protein called HER2 in the urine can help identify children and adolescents with lupus who are at risk of serious kidney complications, a study suggests. While the study is still ongoing, the finding suggests that the use of approved HER2 inhibitors such as Tyverb (lapatinib)…
The levels of galectin-3 binding protein (G3BP) in urine could be used as a biomarker of renal disease activity for systemic lupus erythematosus (SLE) patients with lupus nephritis, according to a study. The study, “Urinary Galectin-3 Binding Protein As a Novel Biomarker of Renal Disease Activity…
Levels of circulating cell-free DNA can potentially be used as a biomarker for assessing disease activity and monitoring treatment effectiveness in patients with systemic lupus erythematosus (SLE), a study shows. The study, “High levels of circulating cell free DNA are a biomarker of active SLE,” was published in…
Determining the activity of an enzyme in the blood could help doctors diagnose and track the progression of lupus, a Chinese study suggests. The research, “Serum adenosine deaminase activity is increased in systemic lupus erythematosus patients and correlated with disease activity,” was published in the journal Immunologic Research. A…
The levels of nitrated nucleosome (NN) in the blood rise at the time of a neuropsychiatric event in some patients with systemic lupus erythematosus (SLE), research from a multi-center, international study shows. However, new studies are required to assess the potential of NN as a biomarker for neuropsychiatric systemic lupus…
A biomarker of hardened arteries makes it eight times more likely that a lupus patient will develop a cardiovascular disease, according to a study. The presence of the marker could prompt lupus patients with no symptoms of heart disease, or who appear to be at low risk of developing it,…
A super-sensitive assay, capable of detecting minute amounts of the immune factor interferon-alpha, will aid physicians in diagnosing systemic lupus erythematosus (SLE) as well as other autoimmune conditions linked to the factor. Interferon-alpha is an extremely potent molecule, and because of this, it is only present in tiny amounts in…
Urinary levels of the protein albumin may help determine the amount of kidney damage in lupus nephritis patients who exhibit few symptoms, according to a study. The finding could help doctors decide which patients need a kidney biopsy. The study, “Urinary Albumin Levels Are Independently Associated With Renal Lesion…