Scientists have created small molecules that can block the activity of SLC15A4, an inflammatory protein — long considered undruggable — that’s known to play a central role in driving lupus and other autoimmune diseases. Further, the team showed that these molecules could reduce inflammation in lupus patient cells and…
RemeGen has received $100 million in private financing to continue advancing RC18 (telitacicept), its lead treatment candidate for autoimmune diseases like systemic lupus erythematosus (SLE) now in a pivotal clinical trial. The funding will also support the China-based company’s early stage treatment discovery platform, help expand its manufacturing…
BioMed X and Merck are establishing a combined research group that will focus on the role of the gut epithelial barrier in the development and progression of autoimmune diseases, including systemic lupus erythematosus (SLE) and multiple sclerosis. This new group will extend the companies’ continuing partnership to…
The idea that the female immune system adapts to accommodate pregnancy could explain why biological females are more likely than males to develop lupus and other autoimmune diseases, a study suggests. The study, titled “The Pregnancy Pickle: Evolved Immune Compensation Due to Pregnancy Underlies Sex Differences in…
A team of scientists from the University of California San Francisco has developed an innovative technique to genetically engineer genes involved in the body’s immune response. This new approach has the potential to revolutionize the way autoimmune diseases, such as lupus, rheumatoid arthritis, cancer, and HIV are treated. …
Infection with the Epstein-Barr virus (EBV) that causes mononucleosis can increase a person’s risk of developing any of seven major autoimmune diseases, including systemic lupus erythematosus, new and possibly ground-breaking research indicates. The study, “Transcription factors operate across disease loci, with…
In this animated video from Lupus U.K., the disease is depicted as an invisible monster. It explains that lupus is an autoimmune disease that rarely displays any visible signs. MORE: Discover how lupus affects blood platelets The invisible nature of the disease makes it difficult for non-sufferers to understand just how debilitating lupus…
A large group study following almost 1 million people for more than six years shows that patients with autoimmune diseases, including systemic lupus erythematosus (SLE), have a significantly greater risk for cardiovascular disease and death. The research, “The Association Between Chronic Immune-Mediated Inflammatory Diseases and Cardiovascular Risk,”…
Lupus is an autoimmune disease where the body attacks healthy tissue. Since lupus affects different areas of the body, there are various symptoms, including joint swelling, rashes, chest pain, fatigue, and light sensitivity. According to Medical News Today, there are a number of ways to help prevent and treat…
Servier and ILTOO Pharma have joined forces with an exclusive license agreement for the development and commercialization of the investigational drug ILT-101 (low-dose interleukin-2) to target systemic lupus erythematosus (SLE) and other autoimmune diseases. The companies expect that results of the ongoing Phase 2 clinical trial (NCT02955615)…