Nimbus Therapeutics, which uses computer analysis to identify and develop therapies for autoimmune diseases like lupus, has established a long-term strategic alliance with Celgene, a company that focuses on immunology. The agreement promises to foster the development of new therapies for diseases triggered by imbalanced immune system responses. Nimbus…
Cognitive impairment is highly prevalent in patients with systemic lupus erythematosus (SLE), a study from Canada finds. The research also addressed the validity of different screening tools for this difficulty in lupus, and found the Montreal Cognitive Assessment (MoCA) may be more suitable that others. The study, “…
Patients with systemic lupus erythematosus (SLE) report high levels of satisfaction when Benlysta (belimumab) therapy was self-administered using an autoinjector, a small study reports. The study, “Patient Evaluation of Satisfaction and Outcomes with an Autoinjector for Self-Administration of Subcutaneous Belimumab in Patients with Systemic Lupus Erythematosus,” was published in…
The presence of anti-SS-B autoantibodies alone was not associated with connective tissue disease (CTD) in daily clinical practice, particularly in the case of primary Sjogren’s syndrome but also lupus patients, a new study shows. The study, “Isolated positive anti-SS-B autoantibodies are not related to clinical features of…
New data from an ongoing Phase 3 clinical trial continues to demonstrate that ImmuPharma‘s Lupuzor is safe for the treatment of systemic lupus erythematosus (SLE) patients. To date, all trial participants have reached the six-month stage, and one out of four have completed…
Japan’s Ministry of Health, Labor and Welfare has approved Benlysta (belimumab) as an add-on therapy to treat adult patients with systemic lupus erythematosus (SLE) who cannot receive or don’t respond to existing therapies. The drug, developed by GlaxoSmithKline (GSK), will be available in two formulations, given via intravenous (IV) or subcutaneous (SC)…
U.K. researchers are establishing a national consortium with a grant of £1.7 million (British pounds) from the Medical Research Council (MRC) to create the world’s largest Immune-Mediated Inflammatory Disease (IMID) Biobank, with more than 40,000 patients. The IMIDBio-UK consortium will incorporate different biobanks and clinical datasets into one single,…
Good gut bacteria might prevent disease processes leading to heart disease in patients with systemic lupus erythematosus, according to a mice study that appeared in the journal PLOS ONE. The findings add to the growing insight that gut bacteria play a key role in controlling the immune system, which…
Daily moderate exercise suppresses lupus-associated kidney inflammation while social stress worsens it, researchers at Ohio State University have found. Their study, “Daily Moderate Exercise Is Beneficial and Social Stress Is Detrimental to Disease Pathology in Murine Lupus Nephritis,” appeared in the journal Frontiers in Physiology.
The lectin pathway of the complement system — a system that enhances the body’s ability to clear invaders — may underlie the clinical manifestation of systemic lupus erythematosus (SLE), new research suggests. The study “Mannose-binding lectin serum levels in patients with systemic lupus erythematosus: association with thrombocytopaenia…