The Alliance for Lupus Research (ALR), a national volunteer health organization dedicated to finding better treatments and ultimately preventing and cure systemic lupus erythematosus (SLE, or lupus) has contributed more than $100 million to research and development for SLE. ALR recently sponsored New York Jets guard Willie Colon’s 1st Annual…
In a recent review paper published in Seminars in Arthritis and Rheumatism entitled “The CD27–CD70 pathway and pathogenesis of autoimmune disease“, researchers examined the role of the CD27 receptor and its ligand protein CD70 in functional changes of autoimmune diseases with particular focus on systemic lupus…
Despite intense research on autoimmune diseases like lupus, little is still known on how the immune system works to attack the patient’s tissues and organs. However, a recent study titled “Neutrophil trails guide influenza specific CD8+ T cells in the airways” and published early this month in the…
In a recent study entitled “Non-Classical monocytes display inflammatory features: Validation in Sepsis and Systemic Lupus Erythematous” published in the Scientific Reports journal, a team of researchers from India presented a robust method of identifying monocytes, a type of white blood cell that is involved in different…
A team of researchers from Argentina and the U.S. have explained how flare-ups in multiple sclerosis patients are intimately related to their melatonin levels, a natural occurring hormone that regulates our sleep/wake cycles – circadian rhythms. The team showed that melatonin alleviates disease symptoms by resetting the immune system, with these…
The Lupus Foundation of America has invited Scottsdale, Arizona’s Mayor, Jim Lane, as its guest of honor during the annual Walk to End Lupus Now fundraiser, the largest lupus walk program in the country, which is set to take place at the Scottsdale Center for the Arts on Saturday, September 19,…
In a recent study, presented during the European League Against Rheumatism Annual European Congress of Rheumatology, a group of Egyptian researchers compared vitamin D levels between patients with systemic lupus erythematosus (SLE) and healthy individuals. The results were clear: vitamin D deficiency and insufficiency is present in SLE patients and vitamin activity is negatively correlated with…
A recently published study led by UK researchers from Imperial College of London (ICL) has shown an association between high levels of saturated fat in the blood and an increase in inflammatory induced tissue damage. The study entitled, “Triglyceride-Rich Lipoproteins Modulate the Distribution and Extravasation of Ly6C/Gr1low…
Lupus is an autoimmune disease, i.e., a disease where the immune system attacks the person’s own body, and it manifests via different symptoms (a key factor frequently delaying the correct diagnosis). Currently without any cure, worldwide experts (from over 80 countries) are meeting in Vienna, Austria, from the 2nd –…
In a recent review paper entitled “Defects in germinal center selection in SLE”, published in Frontiers in Immunology, the authors discuss the mechanisms leading to a deficient selection of auto-reactive B cells in lymph nodes of patients with Systemic Lupus Erythematosus (SLE). Systemic…