A team of researchers from Argentina and the U.S. have explained how flare-ups in multiple sclerosis patients are intimately related to their melatonin levels, a natural occurring hormone that regulates our sleep/wake cycles – circadian rhythms. The team showed that melatonin alleviates disease symptoms by resetting the immune system, with these…
The Lupus Foundation of America has invited Scottsdale, Arizona’s Mayor, Jim Lane, as its guest of honor during the annual Walk to End Lupus Now fundraiser, the largest lupus walk program in the country, which is set to take place at the Scottsdale Center for the Arts on Saturday, September 19,…
In a recent study, presented during the European League Against Rheumatism Annual European Congress of Rheumatology, a group of Egyptian researchers compared vitamin D levels between patients with systemic lupus erythematosus (SLE) and healthy individuals. The results were clear: vitamin D deficiency and insufficiency is present in SLE patients and vitamin activity is negatively correlated with…
A recently published study led by UK researchers from Imperial College of London (ICL) has shown an association between high levels of saturated fat in the blood and an increase in inflammatory induced tissue damage. The study entitled, “Triglyceride-Rich Lipoproteins Modulate the Distribution and Extravasation of Ly6C/Gr1low…
Lupus is an autoimmune disease, i.e., a disease where the immune system attacks the person’s own body, and it manifests via different symptoms (a key factor frequently delaying the correct diagnosis). Currently without any cure, worldwide experts (from over 80 countries) are meeting in Vienna, Austria, from the 2nd –…
In a recent review paper entitled “Defects in germinal center selection in SLE”, published in Frontiers in Immunology, the authors discuss the mechanisms leading to a deficient selection of auto-reactive B cells in lymph nodes of patients with Systemic Lupus Erythematosus (SLE). Systemic…
NEOVACS, a leading biotechnology company focused on an active immunotherapy technology platform (Kinoids) with applications in autoimmune and/or inflammatory diseases, announced it has been granted initial approvals by regulatory agencies and ethics committees in several countries in the European Union for a Phase IIb clinical study of investigational IFNα-Kinoid for patients…
Pregnant women with lupus (a rheumatic autoimmune condition) have an increased risk of transmitting the condition to their newborns, especially if they have lupus or Sjögren’s syndrome along with antibodies to SSA/Ro and/or SSB/La proteins. According to Dr. Jill P. Buyon, M.D., professor of medicine and director of the Division of Rheumatology at NYU,…
The American College of Rheumatology’s (ACR) The Lupus Initiative (TLI) has awarded a one-year, $500,000 grant from the Office of Minority Health (OMH) to expand its established, national education program with development of an evidence-based program model aimed at improved health outcomes for people with lupus living…
Janus Biotherapeutics (Janus), a Boston, Massachusetts based autoimmunity therapeutics company dedicated to development of novel, orally available compounds for treating autoimmune diseases such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), Sjogren’s syndrome, psoriasis, and scleroderma, have announced their entry into a collaboration with multinational pharma firm Roche…