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April 3, 2020April 3, 2020

Phase 3 Results Suggest Low-Dose Prednisone Lowers Flare Risk in SLE Patients in Remission

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People with systemic lupus erythematosus (SLE) who have been in remission for at least a year and take low-dose prednisone as maintenance therapy have less risk of a disease ... Read more

March 27, 2020March 27, 2020

Voclosporin Helps Protect Kidneys in Lupus Nephritis, Phase 3 Trial Shows

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Adding the experimental oral therapy voclosporin to standard treatment is safe, and its use more than doubles complete kidney responses in people with lupus nephritis, results from the Phase 3 ... Read more

March 23, 2020March 23, 2020

LFA Working To Ensure Supply of Lupus Medications for Patients Amid COVID-19

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The World Health Organization (WHO) is launching an international clinical trial to study the use of lupus treatments hydroxychloroquine and chloroquine as potential therapies for pneumonia caused by the ... Read more

March 20, 2020March 20, 2020

GluN2A Protein Subunit in Nerve Cells May Be Treatment Target in SLE, Mouse Study Suggests

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A specific protein subunit — called GluN2A — found in a critical nerve cell receptor is the target of autoantibodies that cause neuron loss and cognitive difficulties in a ... Read more

March 18, 2020March 18, 2020

Voclosporin for Lupus Nephritis Under ‘Rolling’ Review by FDA

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Aurinia Pharmaceuticals announced the start of a rolling submission of its application requesting that voclosporin be approved in the U.S. to treat people with lupus nephritis. In a rolling submission, completed portions ... Read more

March 16, 2020March 16, 2020

Therapy Shows Potential to Block, Not Deplete, B-cells in Phase 1b Trial

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PRV-3279, a potential therapy for people with systemic lupus erythematosus (SLE), durably blocks B-cells to prevent them from producing damaging antibodies, but does not deplete these key immune defense system cells, results ... Read more

March 13, 2020March 13, 2020

Aurinia, NKF Partner for National Kidney Month, Focus on Lupus Nephritis

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Aurinia Pharmaceuticals is again partnering with the National Kidney Foundation (NFK) during National Kidney Month to raise awareness of lupus nephritis (LN) — a type of kidney disease caused by systemic lupus erythematosus, ... Read more

March 12, 2020March 12, 2020

Acthar Gel Eases SLE Exacerbations and Symptoms, Study Reports

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Treatment with Acthar Gel (repository corticotropin injection) may ease exacerbations and symptoms in people with systemic lupus erythematosus (SLE) and other inflammatory disorders, a real-world study reports. About 95% of those ... Read more

March 9, 2020March 9, 2020

Patient-reported Lupus Flares Linked to Disease Severity, Survey Finds

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Taking into account patient-reported lupus flares in clinical practice may help assess disease severity and the economic impact of the disease, including loss of work productivity and hospital care, ... Read more

March 6, 2020March 6, 2020

Lower Income Linked to Increased Risk of Lupus Nephritis, New Study Finds

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Lower income is associated with a significantly higher risk of certain kidney diseases, including lupus nephritis, a new study found. The study, “Socioeconomic Position and Incidence of Glomerular Diseases,” ... Read more

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News

Phase 3 Results Suggest Low-Dose Prednisone Lowers Flare Risk in SLE Patients in Remission

Voclosporin Helps Protect Kidneys in Lupus Nephritis, Phase 3 Trial Shows

LFA Working To Ensure Supply of Lupus Medications for Patients Amid COVID-19

GluN2A Protein Subunit in Nerve Cells May Be Treatment Target in SLE, Mouse Study Suggests

Voclosporin for Lupus Nephritis Under ‘Rolling’ Review by FDA

Therapy Shows Potential to Block, Not Deplete, B-cells in Phase 1b Trial

Aurinia, NKF Partner for National Kidney Month, Focus on Lupus Nephritis

Acthar Gel Eases SLE Exacerbations and Symptoms, Study Reports

Patient-reported Lupus Flares Linked to Disease Severity, Survey Finds

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