News

August 16, 2019

First Patient Dosed in Early Trial Evaluating Provention’s PRV-3279 for SLE

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Provention Bio has dosed the first lupus patient enrolled in the Phase 1b/2 trial testing the safety and pharmaceutical properties of its experimental B-cell-targeted therapy PRV-3279. Results from the ... Read more

August 12, 2019August 12, 2019

Disease Variability Identified as Biggest Hindrance to Lupus Diagnosis and Treatment Advances, ALPHA Project Shows

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An international panel of experts on lupus has defined key issues that need to be overcome — with disease variability being the biggest challenge — to improve the clinical ... Read more

August 9, 2019

Testing for Antibodies Against p40 May Help Diagnose Lupus Earlier, Study Shows

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Systemic lupus erythematous patients with antibodies against the protein LINE-1 p40 are more likely to have active and severe disease, a study shows. Since the presence of antibodies against ... Read more

August 6, 2019August 6, 2019

Pregnancy-associated Changes in Gut Microbiota May Contribute to Lupus Exacerbations, Mouse Study Suggests

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Changes in gut bacteria, or microbiota, during pregnancy and lactation can shift the immune response towards a more pro-inflammatory state that can bolster autoimmune responses and worsen lupus, a ... Read more

August 5, 2019

Sustained SLE Clinical Remission Possible on Lower Doses of Predisone, Study Shows

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A treatment regimen that maximizes the use of hydroxychloroquine, pulse methyl-prednisolone, and methotrexate — while reducing doses of oral prednisone — leads to better outcomes, including prolonged clinical remission, ... Read more

August 2, 2019

Study Yields Interesting Findings About Molecular Development of B-cells in SLE Patients

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B-cells in people with systemic lupus erythematosus (SLE) are distinct from those in healthy people, even at very early stages in B-cell development, a new study shows. The study ... Read more

July 31, 2019

Progentec Granted $1.7M to Validate Measure of SLE Disease Activity

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Progentec, a company developing new diagnostic technologies for chronic conditions, has been awarded $1.7 million to validate its blood biomarker test as an accurate tool for measuring disease activity ... Read more

July 29, 2019

‘Lupus Low Disease Activity State’ Linked to Reduced Healthcare Costs, Study Confirms

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Attaining a low disease state — deemed Lupus Low Disease Activity State or LLDAS — has become a major goal for treatment for people with systemic lupus erythematosus. Researchers ... Read more

July 26, 2019

Resolve Therapeutics Completes Enrollment for RSLV-132’s Phase 2a SLE Trial

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A Phase 2a clinical trial evaluating Resolve Therapeutics‘ investigational treatment RSLV-132 in systemic lupus erythematosus (SLE) has completed patient enrollment, the company announced. The trial has recruited 64 patients with ... Read more

July 24, 2019

Plucked Hair Follicles May Be Useful in Diagnosing Scalp Lupus Erythematosus

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Examining gene expression in hair follicles may be sufficient to diagnose chronic discoid lupus erythematosus (CDLE), a kind of lupus in the scalp, avoiding invasive and expensive scalp biopsies, ... Read more

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News

First Patient Dosed in Early Trial Evaluating Provention’s PRV-3279 for SLE

Disease Variability Identified as Biggest Hindrance to Lupus Diagnosis and Treatment Advances, ALPHA Project Shows

Testing for Antibodies Against p40 May Help Diagnose Lupus Earlier, Study Shows

Pregnancy-associated Changes in Gut Microbiota May Contribute to Lupus Exacerbations, Mouse Study Suggests

Sustained SLE Clinical Remission Possible on Lower Doses of Predisone, Study Shows

Study Yields Interesting Findings About Molecular Development of B-cells in SLE Patients

Progentec Granted $1.7M to Validate Measure of SLE Disease Activity

‘Lupus Low Disease Activity State’ Linked to Reduced Healthcare Costs, Study Confirms

Resolve Therapeutics Completes Enrollment for RSLV-132’s Phase 2a SLE Trial

Plucked Hair Follicles May Be Useful in Diagnosing Scalp Lupus Erythematosus

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