News

August 22, 2017

Damage Outside Blood-Cleaning Areas of Kidneys Can Predict End-stage Disease, Study Indicates

Damage to small tubes in the kidneys and the tissue that surrounds them is a strong predictor that lupus nephritis patients will develop an end-stage renal disease, a New York ... Read more

August 21, 2017August 21, 2017

Inhibitor of Nogo-a Protein Improves Symptoms of Neuropsychiatric Lupus in Mice, Study Shows

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A new study suggests that the protein Nogo-a, known to limit the recovery of neurons after injury, is involved in the development of neurophsychiatric lupus (NPSLE). When this protein was inhibited ... Read more

August 18, 2017August 18, 2017

Lupus Patients Have Increased Risk of Cardiovascular and Metabolic Disease, Study Shows

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Patients with systemic lupus erythematosus have an increased risk for cardiovascular and metabolic diseases — a risk that they share with patients who have other chronic inflammatory conditions, according ... Read more

August 17, 2017

European Initiative Issues New Recommendations for Diagnosis, Treatment of Pediatric SLE

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A European initiative called SHARE has issued new international guidelines for the diagnosis, management, and treatment of childhood-onset systemic lupus erythematosus (cSLE). The recommendations are expected to support uniform, ... Read more

August 14, 2017

Anthera’s Blisibimod Granted Orphan Drug Status for Inflammatory Kidney Disease

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The U.S. Food and Drug Administration (FDA) has granted orphan drug status to the investigative therapy blisibimod for the treatment of immunoglobulin A nephropathy (IgAN), according to Anthera Pharmaceuticals, the ... Read more

August 8, 2017

Dendritic Cells May Hold Key for New Lupus Immunotherapy, Study Reports

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Re-engineering a class of immune cells called dendritic cells (DCs) toward self-tolerance for many of the antigens underlying systemic lupus erythematosus (SLE) may be a potential therapeutic approach to treat ... Read more

August 3, 2017

Clinical Trial Simulations Provide Insight About African-Americans’ Participation

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In a novel approach to better understand factors affecting clinical trials, researchers conducted clinical trial simulations focusing on African-American and lower-income populations. Almost half of all clinical trials are ... Read more

August 1, 2017

24 People with Lupus and Other Autoimmune Diseases Are Receiving KY1005 in Phase 1 Trial

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Twenty-four people with lupus and other autoimmune disorders who signed up for a Phase 1 clinical trial of KY1005 are receiving the antibody therapy, according to its maker, Kymab. KY1005 addresses the ... Read more

July 31, 2017July 31, 2017

SLE Self-Reactive Antibodies May Neutralize HIV Virus, Study Suggests

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Some of the self-reactive antibodies produced in patients with systemic lupus erythematosus (SLE) were found to neutralize HIV, the virus responsible for causing AIDS, thus protecting patients from the disease. ... Read more

July 22, 2017

FDA Approves Self-Injectable Formulation of Benlysta for SLE Patients

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The US Food and Drug Administration (FDA) has approved GSK’s new Benlysta subcutaneous formulation. With the approval, Systemic Lupus Erythematosus (SLE) patients will now be able self-inject Benlysta once ... Read more