Lupkynis (voclosporin) continues to be safe and to protect kidney function when taken for up to three years by patients with lupus nephritis, a kidney complication of lupus. That’s according to the full results from AURORA 2 (NCT03597464), a Phase 3 extension study that evaluated how safe…
The Lupus Research Alliance has named the winners of this year’s Awards to Promote Diversity in Lupus Research, all from underrepresented minority groups who are interested in studying lupus. Four researchers were selected to receive a Career Development Award, which provides up to $600,000 over four years to…
Trethera will use a $0.6 million Small Business Technology Transfer (STTR) grant to advance TRE-515, its lead candidate for systemic lupus erythematosus (SLE). The grant comes from the National Institute for Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), from which the company…
A new project incubating at Duke Advanced Practice Provider Leadership Institute (APPLI) seeks to foster a team approach to lupus care at Duke Health in Durham, North Carolina. The project is being led by Keisha-Gaye O’Garo, a clinical psychologist, and Karen McCain, a psychiatric nurse practitioner, both from…
A type of anti-DNA autoantibodies that also block an enzyme called DNase1L3 may cause more harm to people with systemic lupus erythematosus (SLE) than those that only bind to genetic material, a study has found. These results, the researchers say, shed new light on the origin of SLE, the…
A middle dose of rezpegaldesleukin, an experimental medicine being developed by Nektar Therapeutics, led to clinically meaningful gains in measures of disease activity in people with systemic lupus erythematosus (SLE). That’s according to top-line data from ISLAND (NCT04433585), a Phase 2 clinical study that evaluated how safe…
A test of galectin-3-binding protein (G3BP) levels in the urine is an easy way to distinguish lupus nephritis, an inflammation of the kidneys caused by systemic lupus erythematosus (SLE), from other forms of lupus where the kidneys are not affected, a study suggested. Researchers also observed that protein levels…