Brepocitinib fails to show benefits beyond placebo in Phase 2 trial

Brepocitinib, an investigational oral therapy, failed to show any benefits beyond a placebo in a Phase 2 clinical trial that tested it in adults with moderate to severely active systemic lupus erythematosus (SLE). As such, the trial failed to meet its primary objective, as assessed using the SLE Responder…

Stem Cell Therapy Fails to Improve Lupus Patients’ Kidney Impairment, Study Shows

Umbilical cord-derived stem cells failed to improve lupus patients’ impaired kidney function, according to a small clinical trial in China whose results contrasted with previous studies. The research, “A randomised double-blind, placebo-controlled trial of allogeneic umbilical cord-derived mesenchymal stem cell for lupus nephritis,“ was published in Annals of…