Results of a Phase 3 clinical trial of blisibimod, by Anthera Pharmaceuticals, found that treatment significantly reduces proteinuria — excess proteins in the urine — in patients with systemic lupus erythematous (SLE). Like many B-cell mediated autoimmune diseases, lupus is associated with elevated levels of B-cell activating factor (BAFF). Blisibimod is…
Lupus is an autoimmune disease that can attack any part of the body, including internal organs. The kidneys are commonly affected in lupus patients and can lead to the development of lupus nephritis. We’ve put together a list of five of the most common symptoms of lupus nephritis using information…
Lupus patients with a history of kidney disease, but now in remission, should not be advised against a wanted pregnancy — even if they show serologic activity, or positive anti-double-stranded DNA antibodies and low complement levels (C4), results from the PROMISSE trial show. Women in the study based on these findings, “…
Measuring the level of certain pro-inflammatory cytokines in the blood of patients with systemic lupus erythematosus (SLE) may help to identify those patients with kidney inflammation (nephritis), and so that treatments can begin that might halt the progression to kidney failure. The study, “Serum Cytokines Th1, Th2, and…