Adding anifrolumab to standard-of-care treatment led to a clinically meaningful reduction in disease activity at week 52 in patients with systemic lupus erythematosus (SLE), according to top-line results of a Phase 3 trial. The TULIP 2 study (NCT02446899) assessed the safety and efficacy of AstraZeneca’s anifrolumab in…
Anifrolumab, MedImmune‘s investigational antibody being developed to treat systemic lupus erythematosus, is no better than placebo at reducing disease activity, results from the pivotal TULIP 1 Phase 3 clinical trial show. “The result of this trial is disappointing for patients and the lupus community,” Sean Bohen, MD, PhD, said in…
Patients with systemic lupus erythematosus (SLE) had lower disease activity when they took the investigational treatment anifrolumab along with standard medications, according to a recently completed Phase 2b clinical trial (NCT01438489). Noting the treatment’s potential to target several organs and ease the disease’s symptoms, researchers called the trial “the…