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Infections Can Trigger Lupus Flares, According to New Research

Temple University School of Medicine researchers have discovered how infections cause lupus flares. In a study funded by the Lupus Research Institute (LRI) and the NIH’s National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), Stefania Galluci, PhD, and her team identified a mechanism through which a specific type…

Potential Lupus Treatment, RSLV-132, Shows Positive Results in Early Clinical Test

Resolve Therapeutics has successfully completed a dose escalation study of its candidate drug RSLV-132 targeting systemic lupus erythematosus (SLE). RSLV-132 works by breaking down the RNA found in immune complexes. Increasing evidence shows the importance of RNA bound to autoantibody immune complexes to activate the inflammatory pathway regulated by interferon. The drug…