News

Treatment of systemic lupus erythematosus (SLE) needs to reflect the involvement of particular organs as well as the severity of disease, according to a study presented at the Congress of Clinical Rheumatology Annual Meeting, scrutinizing published clinical trials of lupus. The study advocated giving more weight to clinical experience…

The Alliance for Lupus Research (ALR) partnered with Willie Colon, the former New York Jets offensive guard, for the second Annual Willie Colon Charity Golf Outing fundraiser benefitting the ALR Jean Davis Research Grant. Money raised at the event is used to further ALR-targeted research efforts. Other former National Football League players who attended…

Researchers have identified an enzyme called SHP-2 whose levels are significantly increased in blood samples of lupus patients and in systemic lupus erythematosus (SLE) mouse models, which can become a potential therapeutic target for patients suffering from this disease. The study, “Inhibition of SHP2 ameliorates the pathogenesis of systemic lupus…

The U.S. National Institute of Allergy and Infectious Disease (NIAID) has awarded $225,000 to Karyopharm Therapeutics to advance the development of its SINE nuclear transport compound, KPT-350, to treat neurological, inflammatory and autoimmune diseases. The grant will be used in preclinical trials of the compound as a treatment for  systemic lupus erythematosus (SLE), which will…

Findings from a large “Treat-to-Target” (T2T) study of systemic lupus erythematosus (SLE), focusing on patient and disease characteristics, and factors influencing a low disease activity state — associated with better long-term outcomes —  were presented at the recent  Australian Rheumatology Association Annual Scientific Meeting in Darwin. Treat-to-Target (T2T), an approach used for the design…

Lupus patient organizations are working to launch the World Lupus Federation (WLF), a new coalition aiming to improve life for the more than five million lupus patients worldwide. The WLF will facilitate the efforts of some 200 national groups to promote lupus education, awareness, and advocacy. New members of the WLF’s International Steering Committee are…