News

Lupus Autoimmune B-cells Escape miRNA Quality Control, Study Shows

Scientists at The Scripps Research Institute identified key mechanisms contributing to the generation of autoimmune B-cells that attack the body’s own tissues in diseases like systemic lupus eurythematosus. In a cluster of microRNA (miRNA) molecules, the research team found one factor with exaggerated presence that allows faulty cells to sneak…

I Am a Lupus Warrior

Being that this is my first blog post with y’all, I’ll start out by introducing myself with a warm hello and a virtual hug.   I know at some point we all end up adding labels to people because it can be the easiest way to get a feel for someone’s personality and their…

Arzerra Seen as Alternative for Lupus Patients with Adverse Reactions to Rituxan

Reactions following Rituxan (rituximab) infusions often limit its repeat use in patients with severe systemic lupus erythematosus (SLE), and the alternative B-cell-depleting agent Arzerra (ofatumumab) may be a good option for these people, according to researchers at the Karolinska Institute. Their study, “Ofatumumab treatment in lupus nephritis patients“, published in…

Research into MicroRNA May Lead to New Lupus Therapy, Better Vaccines

New research into a microRNA that helps to produce antibodies offering long-term protection against disease takes science a step close to finding a way to boost vaccine responses, and possibly to understanding how the molecule might be used to counter the development of autoimmune diseases like lupus. The study, “A miR-155–Peli1–c-Rel pathway controls the generation…

Successful Pregnancy with Lupus Requires Careful Monitoring, Study Reports

Pregnancy in patients suffering from systemic lupus erythematosus (SLE) can be complicated by a range of factors affecting both the mother and the fetus, and women with the disease were often advised against becoming pregnant. A research review from Yokohama City University Medical Center researchers, however, shows that optimal monitoring and treatment can improve…

Aurinia to Detail Lupus Studies, Therapies in Aug. 4 Breakfast Meeting for Business Leaders

Aurinia Pharmaceuticals will host a lupus nephritis expert breakfast on Thursday, Aug. 4, from 8:00 a.m. to 9:30 a.m. in New York City, to discuss the results of its latest clinical trial in treating lupus nephritis. Other topics at the breakfast, intended for investors, sales analysts, and business development professionals, include current lupus treatments, disease…

Sengenics’ Immunome Protein Array Platform Has Five New Applications

Sengenics announced five new applications for its patented Immunome Protein Array platform, which has been used in recent studies to discover autoantibody biomarkers for many diseases including lupus. The news came during the Immunomics & Proteomics Symposium held July 25-29, in Brunei and Singapore. Important presenters include world leaders in proteomics including Sengenics’ Chief Scientific Advisor…