News

Blood Biomarkers May Work to Detect and Treat Kidney Disease in Lupus Patients

Metabolic profiles may be used to identify patients with systemic lupus erythematosus, and, more importantly, to distinguish between lupus patients with and without kidney disease. The study, “NMR based serum metabolomics reveals a distinctive signature in patients with Lupus Nephritis,” published in the journal Scientific Reports,…

Wheat Proteins May Trigger Inflammation in Lupus and Other Chronic Conditions

Researchers have found that a group of proteins in wheat may be responsible for triggering inflammation in chronic conditions such as lupus, rheumatoid arthritis, and multiple sclerosis. The protein could also contribute to the development of non-celiac gluten sensitivity. How gluten, another wheat protein, can harm people who are celiac and non-celiac gluten sensitive is…

Genes Newly Linked to Skin Disease May Lead to Better Understanding of Lupus

Researchers identified 23 genes associated with a predisposition for vitiligo, an autoimmune disease characterized by patches of skin and hair that lack pigmentation. Their discovery may lead to a better understanding of other autoimmune conditions, such as lupus. The study, “Genome-wide association studies of autoimmune vitiligo identify 23 new risk loci…

Cutaneous Lupus Erythematosus Patients May Benefit from JAK1 Inhibitors

Inhibiting a branch of the JAK/STAT signaling pathway may be an effective therapy against cutaneous lupus erythematosus (CLE), according to a recent report. The study, “JAK3 as an Emerging Target for Topical Treatment of Inflammatory Skin Diseases,” was recently published in PLOS One. A crucial harmful pathway in inflammatory skin diseases,…

Novel Biomarkers May Help Predict Response to Lupus Nephritis Therapy

Researchers have identified novel biomarkers for lupus nephritis (LN), a disease that affects several patients with systemic lupus erythematosus (SLE), according to a study published in the journal Arthritis & Rheumatology. The authors reported these biomarkers can accurately indicate disease development and predict therapeutic effectiveness. The study is titled “…

Blood Levels of IL-10 May Be Biomarker of Disease Activity in SLE Patients

High levels of the anti-inflammatory cytokine IL-10 are associated with higher disease activity in patients with systemic lupus erythematosus (SLE), a finding that suggests  IL-10 can be a potential blood biomarker for SLE. The study, “Clinical associations of IL-10 and IL-37 in systemic lupus erythematosus,” was published in the journal…

R&B Cover by Lori Jenaire to Benefit Those with Autoimmune Diseases

Singer Lori Jenaire is on a mission beyond sales and charting. With the release of her single — which listed in the Top Five Billboard Hot Singles Sales —  “As You Are,” a remake of the 1978 Pharaoah Sander’s R&B classic, Jenaire is pledging a portion of all proceeds from its…

70% of Lupus Nephritis Patients in Full Remission at Week 24 in Small Study of Voclosporin

Aurinia Pharmaceuticals announced that seven of the 10 patients with lupus nephritis (LN) enrolled in its AURION study, evaluating short-term predictors of clinical response to voclosporin treatment, achieved complete disease remission at 24 weeks. In addition, the company reported that patients who achieved remission at eight weeks continued in remission at 24 weeks.