Aurinia Pharmaceuticals announced that its AURA-LV clinical trial, assessing voclosporin for the treatment of lupus nephritis (LN), has achieved its primary endpoint at its lower dose — complete disease remission at 24 weeks. Prespecified secondary endpoints at both dose levels were also reached in comparison to placebo, including partial remission as measured…
Consumption of foods rich in docosahexaenoic acid (DHA), an omega-3 fatty acid, can prevent the onset of systemic lupus erythematosus (SLE) and possibly other autoimmune diseases, according to a study published in the journal PLoS One. The study, by Melissa Bates from Michigan State University and colleagues, is titled “Silica-Triggered…
The very first time I stepped onto Californian soil, in 2013, I was instantly in love with the different culture, how I was completely immersed in something so foreign to everything I’d ever known. My wanderlust was born. From that day on, I’ve planned my life around my…
The University of Rochester Medical Center in New York will host a 10th Lupus Education Day on Saturday, Oct. 15, providing a forum for people with systemic lupus erythematosus (SLE) and their caregivers to interact and to better understand the latest developments in treating and managing the disease. “This is a great opportunity…
Large-scale analysis of genome-wide gene expression signatures allows researchers to discriminate between patients with active and inactive systemic lupus erythematosus — and could help physicians in adjusting treatment to control disease activity while minimizing the risk of side effects. The study reporting the method, “Clinical Application of a Modular…
The Lupus Research Alliance, together with the John and Marcia Goldman Foundation, funded a study that led to researchers identifying some 150 medications, approved by the U.S. Food and Drug Administration (FDA) for other diseases, that could be promising treatments for systemic lupus erythematosus (SLE). The study, published in the journal…
Patients with systemic lupus erythematosus (SLE) may be at increased risk of incident respiratory failure, according to a nationwide study by Taiwanese researchers. The study, “Effect of Systemic Lupus Erythematosus on the Risk of Incident Respiratory Failure: A National Cohort Study,” published in the journal PLoS One, also…
GlaxoSmithKline (GSK) announced that it has filed applications with U.S. and European regulatory agencies to extend the approval of Benlysta (belimumab) as a treatment for active, autoantibody-positive systemic lupus erythematosus (SLE) to its newer, subcutaneous formulation. The applications draw on positive results from a Phase 3 study in SLE patients treated by injection with the…
Aurinia Pharmaceuticals recently announced that it will host a lupus nephritis (LN) expert breakfast on Friday, Sept. 30, from in New York, to present recently released results from the AURA-LV trial in patients with active LN. The Phase 2b clinical trial (NCT02141672) is a randomized, controlled double-blind study comparing…
A case study found that epilepsy and rapid cognitive decline in an 70-year-old man initially masked — and complicated — diagnosing his central nervous system (CNS) lupus, but once the disease was identified and treated with immunotherapy, his neurological symptoms considerably improved. The study, “Neuropsychiatric Systemic Lupus Erythematosus: A Diagnostic Conundrum,” published…