A tool for measuring patient-reported outcomes, called PROMIS-29, performed rather well in a study attempting to validate the approach in patients with systemic lupus erythematosus and other rheumatic conditions. But the researchers’ endorsement of the tool was cautious, as they detected that most patients tended to score at the worse…
Certain autoantibodies may help identify the small group of patients with systemic lupus erythematosus (SLE) at risk of developing pulmonary arterial hypertension (PAH), and those who are at lower risk of death, according to the findings of a retrospective French study. The research, “Pulmonary Arterial Hypertension Associated…
Newly published findings from two population-based registries in New York City and San Francisco have shed light on racial disparities in the prevalence of lupus in the United States. Data from the Manhattan Lupus Surveillance Program first showed that lupus is more prevalent among Hispanic and Asian women in…
The protein OX40L, produced by immune B-cells, plays a key role in the development of systemic lupus erythematosus (SLE) by activating a T-cell subset involved in autoimmunity, new research has found. Inhibition of OX40L B-cells improved lupus symptoms in mice, suggesting that OX40L is a promising new target for lupus treatment. The…
Uptravi (selexipag) delays the progression of pulmonary arterial hypertension in people with PAH that is associated with connective tissue diseases, including lupus, a Phase 3 clinical trial shows. Patients also tolerate Uptravi well, researchers said. PAH associated with connective tissue disease is also known as PAH-CTD, and PAH associated with lupus…
A 49-year-old woman with severe demyelinating syndrome systemic lupus erythematosus (DS-SLE), where lupus affects the white matter in the brain, was successfully treated with Genentech‘s Rituxan (rituximab), along with other medications. The case report, “Severe neuropsychiatric systemic lupus erythematosus successfully treated with rituximab: an alternative to…
Lupus is more prevalent among Hispanic and Asian women in Manhattan, and those women develop significantly greater organ complications, particularly kidney disease, a study from the NYU School of Medicine shows. The research, “The Incidence and Prevalence of Systemic Lupus Erythematosus in New York County (Manhattan), New…
Sufficient scientific evidence exists to support the switch from bio-originators to biosimilars to treat rheumatic diseases, concluded a task force of experts from 10 countries. Their study, “Consensus-based recommendations for the use of biosimilars to treat rheumatological diseases,” appeared in Annals of the Rheumaetic Diseases.
The Montreal Cognitive Assessment (MoCA) may be a useful clinical tool for screening cognitive impairment in patients with systemic lupus erythematosus (SLE), a new study shows. The study titled, “Performance of Screening Tests for Cognitive Impairment in Systemic Lupus Erythematosus,” was published in the…
A Chicago nursing student with lupus has won Top Products‘ 2017 Single Mother Scholarship. The winner, Tiffani Topps, is attending Chicago State University. Top Products, a website that helps people find quality product and service reviews online, created the scholarship to honor moms whose success stories defy the odds. Growing up…
