News

Discovery of Immune System Messenger May Advance Lupus Treatment

Researchers have identified a previously unknown mechanism by which cells that are infected can signal their neighbors that something is wrong. Understanding how this alarm signal works might lead to new strategies for shutting down harmful immune reactions in diseases like lupus. The study, “Intracellular bacteria engage…

Immune Regulator miRNA-142 Could Advance Cancer, Autoimmune Disease Research

A new study has identified a critical regulator of immunity, called microRNA-142, which could have significant implications for understanding or even treating autoimmune diseases and cancer. The study, “microRNA-142-mediated repression of phosphodiesterase 3B critically regulates peripheral immune tolerance,” was published in The Journal of Clinical Investigation. The…

SLE Patients at Higher Risk for Some Blood Cancers, Study Says

Systemic lupus erythematosus (SLE) patients have a higher risk for certain cancers — including cervical, thyroid, ovarian, and oral cancer, as well as lymphoma, multiple myeloma, and leukemia — than the general population, emphasizing the importance of cancer screening programs as part of SLE management. The findings of the…

Study Finds No Causal Link Between Alcohol Intake and SLE Risk

Alcohol intake does not affect the risk of developing systemic lupus erythematosus (SLE), according to a study. The results contradict previous reports about the protective effects of alcohol against SLE. The study, “Alcohol intake and risk of systemic lupus erythematosus: a Mendelian randomization study,” was published in…

Painful Skin Nodules Are Rare Manifestation of SLE in Children

Panniculitis — a group of conditions that causes painful bumps to appear under the skin — is a rare manifestation of childhood-onset systemic lupus erythematosus (cSLE) that occurs mainly in the first three years of disease, and seems to be an indicator of less severe systemic lupus, a study found.