KZR-616, a selective immunoproteasome inhibitor, is safe, well-tolerated, and effectively reduces disease activity in patients with active systemic lupus erythematosus (SLE), preliminary Phase 1b data show. The findings were presented at the European League Against Rheumatism (EULAR) 2019 Annual Meeting in Geneva, Switzerland, in a poster titled, “…
These days, more than ever, we need community. As a culture, we are experiencing higher levels of stress, greater incidence of isolation, and an increase in the prevalence of autoimmune diseases such as systemic lupus erythematosus, rheumatoid arthritis, and others. Slowly, we are starting…
Only a select few are invited to ring the Nasdaq stock exchange bell. The Lupus Foundation of America (LFA) was among them, taking part in closing ceremonies earlier this month. The foundation’s goal in those June 7 ceremonies was to raise awareness of the unpredictable and often-misunderstood disease and…
Certain rare gene mutations, previously ignored, appear to contribute substantially to the development of lupus, new research found, pointing to the potential for targeted therapies for the condition. The study, “Functional rare and low frequency variants in BLK and BANK1 contribute to human lupus,” was published in …
In studying how mycophenolate mofetil treatment affects immune cells and blood markers in people with systemic lupus erythematosus (SLE), researchers uncovered an immune pathway that may explain why is lupus suppressed by this medication. Their findings might…
Platelet-bound C4d (PC4d), one of Exagen‘s patented biomarkers, may be used along with other available biomarkers to estimate the risk of thrombosis — the formation of blood clots — among people with systemic lupus erythematosus (SLE), a study shows. The study, “Platelet-bound C4d, low C3…
Tofacitinib tablets, a medicine approved to treat rheumatoid and psoriatic arthritis, may work for lessening signs and symptoms of arthritis and skin rash in people with systemic lupus erythematosus (SLE), a…
Michigan Medicine researchers were granted up to $10.2 million by the Autoimmunity Centers of Excellence (ACE) to develop new projects seeking treatments for autoimmune diseases including lupus. In particular, the team from the University of Michigan’s academic medical center is focused on exploring the relationship between molecular targets…
In observance of World Lupus Day and Lupus Awareness Month, Aurinia Pharmaceuticals has announced disease awareness and educational initiatives aimed at supporting patients with lupus nephritis, a serious complication of systemic lupus erythematosus (SLE). World Lupus Day was May 10, and Lupus Awareness Month is marked…
A comprehensive report co-led by pharmaceutical company GSK underscores the need to enhance care for those living with lupus, and to raise awareness about the disease. The release of the report, titled “A Vision for Lupus,” was timed to World Lupus Day on May 10. Coordinated by…