Results from a recent study published in the Journal of Rheumatology revealed that patients with systemic lupus erythematosus (SLE) who have low blood levels of prescribed hydroxychloroquine were more likely to have high disease activity. Hydroxychloroquine (HCQ) is in a class of drugs called antimalarials and is…
A new article published by Spanish researchers focuses on whether extracellular vesicles may be used to detect and monitor systemic lupus erythematosus. The work, titled “Extracellular Vesicles as Biomarkers of Systemic Lupus Erythematosus,“ appeared August 25th in the journal Disease Markers. Systemic lupus erythematosus (sometimes called lupus for short)…
In a new study entitled “Association of BAFF, APRIL serum levels, BAFF-R, TACI and BCMA expression on peripheral B-cell subsets with clinical manifestations in systemic lupus erythematosus” researchers investigated the role of B cells’ cytokines and receptors in the pathogenesis and development of systemic lupus erythematosus (SLE). The…
The leading organization in the U.S. dedicated to addressing lupus, The Lupus Foundation of America, has just revealed the recipients of five research grants, awarded under the Foundation’s commitment to support lupus-focused researchers in conducting clinical trials necessary to better understanding and eventually curing this life-altering autoimmune disease. “The researchers…
A history of thrombocytopenia is a strong predictor of diffuse alveolar haemorrhage (DAH) in patients with systemic lupus erythematosus, according to the results of a recent study published in the journal Lupus, Science & Medicine. Systemic lupus erythematosus (SLE) is an autoimmune disease in…
In a recent study entitled “Systemic lupus erythematosus complicated by diffuse alveolar haemorrhage: risk factors, therapy and survival” researchers performed the first study investigating the risk factors for diffuse alveolar haemorrhage in systemic lupus erythematosus and how it impacts patients’ therapy responses and outcomes. The study was published…
A recent study funded by the NIH/NIAMS, revealed data that will lead to a further understanding of why pregnant women with systemic lupus erythematosus (SLE) are at higher risk for adverse pregnancy outcomes (APO), including preeclampsia, placental insufficiency, fetal death, miscarriages, and other complications. The study entitled, “Biomarkers Measured…
In a recent study, researchers from University Hospital of Split, Croatia investigated the relationship between Vitamin D, Interferon-gamma (INF-gamma) and Estradiol in females of childbearing age with inactive Systemic Lupus Erythematosus (SLE). The paper entitled “Relationship between vitamin D, IFN-c, and E2 levels in systemic lupus erythematosus” was…
In a recent study entitled “Hyperactivation and in situ recruitment of inflammatory Vδ2 T cells contributes to disease pathogenesis in systemic lupus erythematosus” scientists discovered that the biggest human γδ T cell subset, the Vδ2 T cells present in peripheral blood, are key mediators of tissue injury…
Studies have revealed there is a gap between what lupus patients experience and what they tell their clinicians with results from a recent survey showing that closing this gap may lead to better communication and improved clinical management of the disease. The 2014 online survey funded and developed by GSK included 905 global respondents…