Researchers identified that a single nucleotide polymorphism in the sequence of the CD40 gene, a gene with key functions in immune diseases, is associated with susceptibility to systemic lupus erythematosus. The study entitled “The association of CD40 polymorphisms with CD40 serum levels and risk of systemic lupus erythematosus” was…
Systemic Lupus Erythematosus (SLE) is an autoimmune disease characterized by a misdirected attack of the immune system against the body’s own organs. Disease origins are quite complex and still not fully understood, hampering SLE’s cure. Due to its systemic nature, SLE causes a wide array of clinical symptoms, complicating its…
The University of Rochester Medical Center’s (UR Medicine) Lupus Clinic is preparing for its ninth annual Lupus Education Day, which is running on Saturday, October 31, 2015, at 3:30 p.m. at the Helen Wood Hall, 255 Crittenden Blvd. Local patients, their loved ones, and caregivers are all invited to this free…
XTL Biopharmaceuticals Ltd. and Yeda Research and Development Company Ltd. have strengthened their collaboration to develop a new therapy for systemic lupus erythematosus (SLE), called hCDR1. The two companies recently signed an amended agreement altering the development milestones featured in the License Agreement signed…
Mallinckrodt Pharmaceuticals recently announced that results from a pilot clinical study for its H.P. Acthar Gel will be presented during the 2015 Annual Meeting of the American College of Rheumatology (ACR) that will take place in San Francisco from 7th until the 11th of November. The pilot…
Results from a recent study published in the Journal of Rheumatology revealed that patients with systemic lupus erythematosus (SLE) who have low blood levels of prescribed hydroxychloroquine were more likely to have high disease activity. Hydroxychloroquine (HCQ) is in a class of drugs called antimalarials and is…
A new article published by Spanish researchers focuses on whether extracellular vesicles may be used to detect and monitor systemic lupus erythematosus. The work, titled “Extracellular Vesicles as Biomarkers of Systemic Lupus Erythematosus,“ appeared August 25th in the journal Disease Markers. Systemic lupus erythematosus (sometimes called lupus for short)…
In a new study entitled “Association of BAFF, APRIL serum levels, BAFF-R, TACI and BCMA expression on peripheral B-cell subsets with clinical manifestations in systemic lupus erythematosus” researchers investigated the role of B cells’ cytokines and receptors in the pathogenesis and development of systemic lupus erythematosus (SLE). The…
The leading organization in the U.S. dedicated to addressing lupus, The Lupus Foundation of America, has just revealed the recipients of five research grants, awarded under the Foundation’s commitment to support lupus-focused researchers in conducting clinical trials necessary to better understanding and eventually curing this life-altering autoimmune disease. “The researchers…
A history of thrombocytopenia is a strong predictor of diffuse alveolar haemorrhage (DAH) in patients with systemic lupus erythematosus, according to the results of a recent study published in the journal Lupus, Science & Medicine. Systemic lupus erythematosus (SLE) is an autoimmune disease in…