Patients with systemic lupus erythematosus (SLE) who develop pneumonia have a high risk of adverse prognosis, according to a new study. The findings also revealed that common scales of pneumonia severity can misclassify cases of SLE and pneumonia as low risk. The research, “Pneumonia in patients…
A series of recently identified small molecules targeting a protein called NR2F6 could lead to new treatments for autoimmune diseases such as lupus, according to Regen BioPharma. NR2F6 is a type of molecule called transcription factor that suppresses gene expression — the transcription of DNA into RNA, the…
Virgin olive oil, especially its phenol components, showed anti-inflammatory properties in mice with systemic lupus erythematosus (SLE) and in human immune cells, according to a new Spanish study. The findings suggest future use in SLE treatment. The research, “Virgin olive oil and its phenol fraction modulate monocyte/macrophage…
At the time of diagnosis, systemic lupus erythematosus (SLE) patients already show signs of heart impairment, even before any symptoms of chest discomfort, a new imaging study shows. The findings indicate that more lupus patients could receive timely cardiac treatment, according to the researchers from China. The study, “…
Interferon-kappa (IFN-κ), an immune response regulator, is a key mediator of skin lesions and UV light sensitivity in cutaneous lupus erythematosus patients, a study reports. Its researchers suggest that blocking IFN-κ with a medication used to treat rheumatoid arthritis may be beneficial. The study, “Photosensitivity and type…
The Lupus Research Alliance awarded Novel Research Grants to two University of Alabama at Birmingham (UAB) researchers who will use the funds to explore potential targeted treatments for lupus. Besides UAB’s Andre Ballesteros-Tato, PhD, and Frances Lund, PhD, seven other researchers in the U.S. were awarded…
DxTerity Diagnostics’ LIFT study supports the use of social media to rapidly enroll lupus patients for clinical trials, as well as ensuring the accuracy of self-reported data and home-based collection of blood samples, according to the company. The research supporting that assertion will be shown at the…
Early treatment to reduce disease activity and prevent irreversible organ damage in pediatric systemic lupus erythematosus (pSLE) patients should be strongly considered, according to new study. The research, “Pediatric Systemic Lupus Erythematosus: Learning From Longer Follow Up to Adulthood,” appeared in the journal Frontiers in…
A type of immune cell that protects against viruses and cancer may worsen systemic lupus erythematosus (SLE) and trigger disease flares, a recent study with mice suggests. Led by researchers at the U.K.’s Imperial College London, the study, “C1q restrains autoimmunity and viral infection by…
Systemic lupus erythematosus (SLE) is a major cause of death in young women that goes largely unrecognized due to its exclusion from an annual nationwide ranking, a new U.S. study shows. Based on these findings, researchers believe that public health and research programs dedicated to the disease are warranted, and…