Defects that disrupt the digestion of dead cells can result in a lupus-like autoimmune disorder, according to a study titled “Noncanonical autophagy inhibits the autoinflammatory, lupus-like response to dying cells” and recently published in the journal Nature by scientists at St. Jude Children’s Research Hospital.
Researchers from St. Jude Children’s Research Hospital in Memphis, Tennessee, in collaboration with several other institutions, published findings from a lupus study in which they discovered a new approach to controlling the inflammation and tissue damage that is a hallmark of the chronic autoimmune disorder. The study, “Noncanonical autophagy…
Japanese researchers reported a rare case of idiopathic intracranial hypertension (IIH) accompanying the onset of systemic lupus erythematosus (SLE) in a patient. The study, “Bilateral Abducens Nerve Palsy due to Idiopathic Intracranial Hypertension as an Initial Manifestation of Systemic Lupus Erythematosus,” was published in Internal Medicine. IIH is a syndrome…
Rheumatology Associates, one of the country’s largest rheumatology specialty practices, announced it has recruited Dr. Padmapriya Sivaraman, the 15th board-certified rheumatologist to join the team and increasing office locations to eight with a new office in North Richland Hills, a suburb of Fort Worth, Texas. Rheumatology Associates, founded in 1975,…
Texas researchers found that neutrophils, a type of immune cell, release oxidized mitochondrial DNA, triggering immune reactions in systemic lupus erythematosus (SLE). The findings provide insights into key disease mechanisms, which might be employed in the development of new therapies for this complex and devastating disease. The research team at…
A research team from the University of California, Los Angeles, has shown that certain types of gut bacteria might be crucial in reducing both cancer and inflammation, a finding with long-reaching implications for diseases with an inflammatory component, such as lupus. Intestinal bacterial flora holds both beneficial species and those with…
French company NEOVACS announced that its Investigational New Drug (IND) application for IFNα Kinoid in lupus, now in Phase 2b development, was approved by the South Korean Health Authority. NEOVACS was established in 1993. Today, the biotech is a leader in active immunotherapy technology platforms (Kinoids) for autoimmune and/or inflammatory diseases. NEOVACS…
Patients with systemic lupus erythematosus (SLE) showed significant improvements and decreased disease severity when treated with a combined therapy of belimumab and standard of care measures for up to 24 months, according to results of a two-year study. The study, “Response to belimumab among patients with systemic…
A new edition of “The Autoimmune Connection: Essential Information for Women on Diagnosis, Treatment and Getting on with Your Life” received praise from the American Autoimmune Related Diseases Association (AARDA), which called the book “the ultimate resource for women with autoimmune diseases.” Written by the award-winning journalist Rita Baron-Faust and lupus…
A study published in the Journal of Experimental Medicine demonstrates that a particular cell-signalling protein is crucial for the formation of autoreactive B-cells in systemic lupus erythematosus (SLE), but not for the formation of B-cells fighting infections. The finding of this autoimmune mechanism opens up the possibility for the development…