News

DN2 B-Cells at Heart of Lupus Disease Activity, Study Suggests

DN2 B-cells — a subset of immune B-cells that are rare in healthy individuals, but extremely common in patients with systemic lupus erythematosus (SLE) — play a critical role in the production of harmful autoantibodies and lupus activity, a study reports. Conducted by a team of researchers at the Emory…

Childhood SLE Has Major Impact in Adulthood, Dutch Study Shows

People with childhood-onset systemic lupus erythematosus (cSLE) develop significant disease-associated damage early in life and have lower quality of life in their adulthood, without achieving medication-free remission, according to a recent Dutch study. The study, “Long‐term clinical outcomes in a cohort of adults with childhood‐onset Systemic Lupus…