Early studies of an endocannabinoid-based treatment for cutaneous lupus erythematosus (CLE) showed that it eased skin lesions, according to Hoth Therapeutics, which developed the therapy. Endocannabinoids are cannabis-like molecules naturally produced by the human body, with effects…
People with systemic lupus erythematosus (SLE) who received more quality clinical care report lower disease activity, slower accumulation of disease-related damage, and a higher physical health-related quality of life, a study finds. The analysis identified parameters that led to improved self-reported health outcomes,…
The Lupus Research Alliance (LRA) has launched an international grant program to unravel the complexity of lupus and to bring more focus to personalized treatments. Called the Global Team Science Award, the program will provide up to three grants, totaling up to $3 million each, over three years.
Elevated blood levels of a marker called galectin-9 may help identify people with systemic lupus erythematous lupus (SLE) who have more active disease and organ damage, a study suggests. The study “Galectin-9 as a biomarker for disease activity in systemic lupus erythematosus” was published in the journal…
The Lupus Foundation of America (LFA) is partnering with Lupus Canada to fund the Lupus Canada Catalyst Award that supports research projects with potential to advance the field and improve the lives of people living with lupus. The award will be given to one researcher (a…
A newly identified genetic signature may provide clues into the mechanisms underlying systemic lupus erythematosus (SLE), and open new potential avenues to personalized treatments. The research, “Integrated, multi-cohort analysis reveals unified signature of systemic lupus erythematosus,” was published in the journal JCI Insight. Gene expression…
Upper limb exercise lowers pain and improves hand function, daily activity performance, and quality of life in people with systemic lupus erythematosus (SLE), according to a pilot clinical trial. The trial’s results, “The impact of upper limb exercise on function, daily activities and quality of life in…
DNA vaccination with heat shock protein 70 (HSP70) eased inflammation, boosted immune regulation, delayed kidney disease and prolonged life in a mouse model of systemic lupus erythematosus (SLE), a study found. While vaccination with HSPs — stress-induced proteins involved in protein regulation and immune response — has…
Pregnancy is not associated with increased chronic damage in women with systemic lupus erythematosus (SLE), regardless of when they’re diagnosed with the autoimmune disease, according to a Japanese study. While these findings may help alleviate fears about childbearing for these women, an SLE diagnosis does put them at…
Hardening of the kidney arteries, a condition called renal arteriosclerosis, is detected two decades earlier in people with lupus nephritis compared with healthy individuals, a study shows. The study, “High Burden of Premature Arteriosclerosis on Renal Biopsies in Incident Lupus Nephritis,” was published in the journal…