News

UAB Researchers Develop a Decision Aid Program on Lupus Therapy Options

Researchers at the University of Alabama at Birmingham (UAB) are currently enrolling participants to conduct a study, funded by the Patient-Centered Outcomes Research Institute, aimed at helping minority women suffering from lupus nephritis make an informed decision concerning available therapies. Systemic lupus erythematosus (SLE) is an autoimmune…

Regulatory T Cell Deficient Mice Develop Lupus-Like Disease

A new study showed that mice deficient in regulatory T cells develop systemic autoimmune disease similar to lupus. The study entitled “Regulatory T cell deficient scurfy mice develop systemic autoimmune features resembling lupus-like disease” was published in Arthritis Research & Therapy. Scurfy mice do…

Plasma Cells Important in Lupus-Prone Mouse Model

A German team focused on the study of lupus recently evaluated the behavior and lifecycle of long-lived plasma cells (LLPCs), which are a part of the disease systemic lupus erythematosus. The study, “Long-lived Plasma Cells Are Early and Constantly Generated in New Zealand Black/New Zealand White…

T Cell Metabolism Influences Signs of Lupus

Metformin, a metabolic drug approved to treat individuals with type 2 diabetes, may also be useful to treat lupus, according to a new study from University of Florida, published in Science Translational Medicine. The study, “Normalization of CD4+ T Cell Metabolism…

Lupus Research Institute Announces Winners of Novel Research Grants

A private supporter of novel lupus research, the Lupus Research Institute (LRI) is celebrating its 15th anniversary with the announcement of a series of grants awarded in recognition of new talent, diversity and excellency. Twelve Novel Research Grants were awarded within the categories of “Strategies for Better, Safer Treatments,” “Innovative Technologies…