Neovacs recently announced that it has signed an exclusive licensing contract granting Chong Kun Dang (CKD) Pharmaceutical Corp. of Seoul the right to market IFNα-Kinoïd, Neovacs’ anti-interferon alpha (IFNα) therapeutic vaccine being developed for the treatment of systemic lupus erythematosus (SLE), in South Korea. Lupus is considered an orphan disease in South…
Lupuzor, a non-immunosuppressant therapy for lupus created by Dr. Sylviane Muller’s team at the CNRS Immunopathologie et Chimie Thérapeutique laboratory, is progressing to a Phase 3 clinical trial, the last stage before possible market approval. Several American and European physicians and investigators recently gathered in Paris to discuss the launch of…
Systemic lupus erythematous (SLE) results from a mistaken response of the body’s immune system against healthy tissue affecting several organs such as skin, kidneys and brain. The underlying causes of SLE remain unknown although several evidences point towards an important role of gut microbes, also known as gut microbiota. Researchers…
A recent review summarized the current knowledge on how unbalanced T-cell signaling characterizes systemic lupus erythematosus (SLE) disease. The review study, titled “Disturbed T Cell Signaling and Altered Th17 and Regulatory T Cell Subsets in the Pathogenesis of Systemic Lupus Erythematosus,” was published in the journal Frontiers in…
Deficiency of a specific form of vitamin D (25(OH)D3) is associated with and independently predicts worse cognitive function in systemic lupus erythematosus (SLE) patients, according to a study in the journal PLOS One. The report is titled “25-Hydroxyvitamin D3 Deficiency Independently Predicts Cognitive Impairment in Patients with Systemic Lupus Erythematosus.” SLE…
ImmunArray, a molecular diagnostics company developing blood-based tests to support the diagnosis and management of acute and chronic immune and neurodegenerative diseases, has announced that it is making its “rule-out” test for systemic lupus erythematosus (SLE) available throughout the United States. The company’s SLE-key Rule-Out Test® is a cost-effective blood test…
New research found that a specific set of immune cells named plasmacytoid dendritic cells (pDCs), long believed to cause lupus disease, actually did not contribute to late-stage lupus in a mice model. The paper, which has potential implications for future disease treatment, was published in The Journal of Immunology and is titled…
Environmental factors, like the DNA sequence itself, can alter the way genes are read. These differences, known as epigenetics, may contribute to differences in lupus susceptibility among individuals. Here, a research team at the University of Michigan investigated whether these differences could explain a higher tendency to develop lupus in people of…
The “Moving Forward Together to Fight Lupus” gala dinner celebrated the upcoming merging of the Alliance for Lupus Research (ALR), the Lupus Research Institute (LRI), and S.L.E. Lupus Foundation. The event — the world’s leading lupus fundraiser — collected close to $3 million for groundbreaking research that promises to…
More than 3,000 scientific abstracts spanning the latest in lupus research were presented at the recent American College of Rheumatology (ACR) annual meeting in San Francisco, which brought together nearly 17,000 healthcare providers and researchers in the fields of rheumatology and immunology. According to an article written by Anita Roach, MS, manager…