Genes regulating the growth factor VEGF signaling pathway are linked to the presence of mouth ulcers in people with systemic lupus erythematosus (SLE), according to a study presented at the European League Against Rheumatism Annual Congress (EULAR 2016) in London on June 10. The finding gives scientists a clue…
Various ethnic groups differ in what specific symptoms of systemic lupus erythematosus (SLE) they display — a difference that might be linked to the presence of different immune factors, according to a new study. Understanding how ethnicity might influence these differences can pave the way for treatments that are better…
Treatment of systemic lupus erythematosus (SLE) needs to reflect the involvement of particular organs as well as the severity of disease, according to a study presented at the Congress of Clinical Rheumatology Annual Meeting, scrutinizing published clinical trials of lupus. The study advocated giving more weight to clinical experience…
Disrupted neuroimmune signaling contributes to cognitive problems in neuropsychiatric systemic lupus erythematosus (SLE), according to a study presented at the Congress of Clinical Rheumatology 2016 Annual Meeting, reported by Healio Rheumatology. These new insights into the molecular mechanisms of lupus might provide targets for the development of therapies for…
The American Autoimmune Related Diseases Association (AARDA), celebrating its 25th year, recently announced its #AutoimmuneHeroes for April, which is national volunteer month in the U.S. The AARDA campaign honors those individuals who have supported the group’s work throughout the years. Those spotlighted in AARDA’s #AutoimmuneHeroes campaign are people and organizations contributing…
Rheumatology Associates, one of the country’s largest rheumatology specialty practices, announced it has recruited Dr. Padmapriya Sivaraman, the 15th board-certified rheumatologist to join the team and increasing office locations to eight with a new office in North Richland Hills, a suburb of Fort Worth, Texas. Rheumatology Associates, founded in 1975,…
Texas researchers found that neutrophils, a type of immune cell, release oxidized mitochondrial DNA, triggering immune reactions in systemic lupus erythematosus (SLE). The findings provide insights into key disease mechanisms, which might be employed in the development of new therapies for this complex and devastating disease. The research team at…
A research team from the University of California, Los Angeles, has shown that certain types of gut bacteria might be crucial in reducing both cancer and inflammation, a finding with long-reaching implications for diseases with an inflammatory component, such as lupus. Intestinal bacterial flora holds both beneficial species and those with…
A new edition of “The Autoimmune Connection: Essential Information for Women on Diagnosis, Treatment and Getting on with Your Life” received praise from the American Autoimmune Related Diseases Association (AARDA), which called the book “the ultimate resource for women with autoimmune diseases.” Written by the award-winning journalist Rita Baron-Faust and lupus…
A study published in the Journal of Experimental Medicine demonstrates that a particular cell-signalling protein is crucial for the formation of autoreactive B-cells in systemic lupus erythematosus (SLE), but not for the formation of B-cells fighting infections. The finding of this autoimmune mechanism opens up the possibility for the development…