Author Archives: Magdalena Kegel

Lupus Research Institute Announces 2016 Research Grants

The Lupus Research Institute (LRI) recently announced this years’ research grants awarded to systemic lupus erythematosus (SLE) researchers. The topics vary, but all strive to either present a better understanding of why people develop lupus or to improve treatment for the disease. Two projects will investigate the link between bacteria…

Key Molecule in Lupus-linked Gene Identified, Opening New Therapy Possibilities

Yale researchers have discovered a new transcription factor governing the production of a gene related to conditions such as systemic lupus erythematosus (SLE). The discovery opens up the possibility of more personalized SLE treatment. The study, titled “Transcription factor ICBP90 regulates the MIF promoter and immune susceptibility locus“ and published in the …

Lupus Inflammation Linked to Fungal Infection May Have Control Mechanism

A recent study has identified two novel substances — an antioxidant and an anti-inflammatory agent — that can control the excessive inflammatory response to fungal infection often seen in patients with systemic lupus erythematosus (SLE). Earlier studies have shown that invasive fungal infection (IFI) with the fungus Candida albicans can be life-threatening for SLE patients.

SLE Biomarker Assay Appears to Overcome Disease’s Heterogeneity

The development of new drugs to treat systemic lupus erythematosus (SLE), in comparison to autoimmune diseases like rheumatoid arthritis, has been excruciatingly slow. Benlysta (belimumab) is the rare exception, the only  SLE drug approved by the U.S. Food and Drug Administration (FDA) in the past 50 years. A biomarker assay for SLE…