Treatment with upadacitinib led to a significant reduction in disease activity for people with moderate-to-severe systemic lupus erythematosus (SLE) in a Phase 2 clinical trial, according to top-line results announced by its developer, AbbVie. Based on these positive results, AbbVie now is planning to advance upadacitinib to Phase 3 clinical…
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A type of anti-DNA autoantibodies that also block an enzyme called DNase1L3 may cause more harm to people with systemic lupus erythematosus (SLE) than those that only bind to genetic material, a study has found. These results, the researchers say, shed new light on the origin of SLE, the…
Living with chronic illness and being immunosuppressed makes things like a cold or the flu hard to manage, says columnist Kristiana Page.
Lupus is an autoimmune inflammatory disease that can affect multiple systems in the body.
While the cause of lupus is often unknown, it is possibly due to a combination of genetics and the environment.
Lupus affects people in different ways, and symptoms vary among patients. Symptoms come and go during periods called flares.
