A combination of specific biomarkers — circulating immune complexes (CIC) and interleukin-6 (IL-6) — may help better predict disease activity in patients with systemic lupus erythematous (SLE), a recent study suggests. The study, “The model of circulating immune complexes and interleukin-6 improves the prediction of disease activity in…
A new study from Harvard University has discovered some of the mechanisms behind why and how immune cells attack their own body in autoimmune diseases such as systemic lupus erythematosus (SLE). The study titled, “Clonal Evolution of Autoreactive…
In a novel approach to better understand factors affecting clinical trials, researchers conducted clinical trial simulations focusing on African-American and lower-income populations. Almost half of all clinical trials are unable to recruit their target sample size. Additionally, dropout of patients during the trial can be as high as 30 percent.
Many systemic lupus erythematous (SLE) patients suffer from vocal disorder, or dysphonia, and should get voice therapy to improve the overall quality of their lives. So argues an article, “Voice disorder in systemic lupus erythematosus,” that recently appeared in the open-access journal PLOS One. Back in the 1950s, people with SLE…
A new study reports that eculizumab may be effective in the treatment of certain patients with systemic lupus erythematous (SLE) with renal (kidney) involvement, a condition called lupus nephritis (LN). In the study, “Expanding the therapeutic options for renal involvement in lupus: eculizumab, available evidence,” published in the journal Rheumatology…