A research team from the University of Dundee recently discovered that a mutation in the protein ABIN1 mediates chronic inflammation and is associated with the development of cardiovascular disease. The results, which have important clinical applications for chronic inflammatory conditions such as systemic lupus erythematous (SLE) and rheumatoid arthritis…
Applications for a series of grants from the National Research Program of the Lupus Foundation of America are currently open for investigators working on lupus-related research. The program is intended to fund critical areas of lupus scientific research, such as environmental triggers of the disease and health…
A new project is being launched by George Freeman MP, the British Parliamentary Under Secretary of State for Life Sciences in collaboration with several academic facilities and industry partners to improve treatment of systemic lupus erythematosus (SLE) in the UK. The MAximizing Sle ThERapeutic PotentiaL by Application of Novel and Stratified…
Despite ongoing efforts, there are still several gaps regarding lupus specificity in the Systemic Lupus International Collaborating Clinics (SLICC) network, according to a study that analyzed the recently reviewed criteria of the system. SLICC-12, the new set of criteria established in 2012 to classify systemic lupus erythematosus (SLE), was recently examined for the first…
Three lupus organizations are joining efforts to support the advancement of lupus research by granting the Lupus Insight Prize, a recognition of major, novel insights and/or discoveries with the potential to alter the thinking on lupus and high probability of creating further progress in the diagnosis and treatment of the condition. The prize will be granted…
A recent study conducted by a team of researchers from Taiwan found that patients with Systemic lupus erythematosus (SLE) who are treated with a specific dose of an antimalarial drug UCQ) are less prone to develop diabetes mellitus. However, those SLE patients that are threated with high-dose glucocorticoids are…
A team of researchers from Taiwan found that patients with systemic lupus erythematosus (SLE) have higher levels of T helper 17 cells than healthy controls, thus encouraging research in IL-17/IL-17R blockades as a potential treatment targets for SLE. The study entitled “Increased Th17 cells in flow…
Systemic lupus erythematosus (SLE) is an immune multi-systemic autoimmune condition that mainly affects young women. Current evidence from population-based studies and randomized controlled trials indicated the onset of SLE and lupus flares is triggered by various environmental factors, such as cigarette smoke, alcohol, occupationally- and non-occupationally-related chemicals, ultraviolet light,…
Christopher Sjöwall from the Rheumatology/AIR Department of Clinical and Experimental Medicine at Linköping in Sweden and colleagues, evaluated the performance of the Systemic Lupus International Collaborating Clinics (SLICC) criteria created in 2012 (SLIC-12) in a European population of patients with systemic lupus erythematosus (SLE). The study…
A clinical review entitled “Mucocutaneous manifestations in juvenile-onset systemic lupus erythematosus: a review of literature” was recently published in the journal Pediatric Rheumatology. Juvenile-onset systemic lupus erythematosus (JSLE) is a common systemic autoimmune connective tissue condition that affects children. Estimations of JSLE are of…