XTL Biopharmaceuticals Ltd. announced it accepted an invitation to join Lupus Foundation of America (LFA)’s Corporate Advisory Council (CAC). XTL is a clinical-stage biotech dedicated to developing pharmaceutical products to treat autoimmune diseases such as lupus. The biotech’s lead drug candidate, hCDR1, is a top-quality clinical asset for the…
Aurinia Pharmaceuticals has completed the initial analysis of voclosporin in its AURION trial, an open label, single arm, exploratory trial examining patients with active lupus nephritis (LN) taking voclosporin 23.7 mg. twice daily in combination with standard of care, mycophenolate mofetil, and corticosteroids. The study is assessing biomarkers of disease…
Research conducted on medical records from over a quarter million adult patients found that African-Americans with connective tissue diseases were twice as likely to suffer complications that increase the risk of a heart attack, stroke, or death. The study, “The Prevalence of Atherosclerosis in Those with…
Lupus during pregnancy increases the likelihood of health complications for women and their babies, according to a study, “What to expect when expecting with SLE: A population-based study of maternal and fetal outcomes in SLE and pre-SLE,” published in the journal Arthritis Care and Research. Adverse pregnancy outcomes…
Aurinia Pharmaceuticals, Inc., has announced its AURA-LV clinical study has completed enrollment and will be treating a total of 265 lupus patients, surpassing its target of 258 patients. AURA-LV (Aurinia Urine protein Reduction in Active Lupus nephritis) is a Phase 2b is randomized, controlled, double-blind clinical trial to compare the efficacy of voclosporin…
Neovacs and Stellar Biotechnologies have collaborated to form a new biotech company called Neostell SAS. Neovacs will own 70 percent of the new company and Stellar Biotechnologies will own the remaining 30 percent. Neovacs is a European leader in immunotherapies developed to treat autoimmune diseases. It’s lead active immunotherapy candidate is IFNα-Kinoid,…
Systemic lupus erythematosus (SLE) patients may be at a higher risk of seizures if they have a history of psychosis, neuropathy, proteinuria, or are currently using corticosteroids — among other factors — according to a study recently published in the Journal of Rheumatology, titled “Predictors of Incident Seizure in Systemic…
XTL Biopharmaceuticals has announced it has submitted the full protocol for its advanced stage clinical trial of hCDR1 in the treatment of systemic lupus erythematosus (SLE, commonly referred to as lupus) to Yeda Research and Development Company in Israel. According to the Phase II clinical study titled “Safety…
Neovacs announced it has concluded a four-year, €5 million ($5.5 million) non-dilutive funding agreement to finalize clinical development and start the production process for its therapeutic IFN Kinoid vaccine. The funding, in the form of grants and repayable advances, came through a decision of The General Commission for Investment, operated by Bpifrance, a subsidiary of the French…
Dutch biopharmaceutical company argenx recently announced the completion of the dose-escalation stage of a Phase 1 clinical trial exploring its drug candidate ARGX-113, a potential breakthrough therapy for treatment of exacerbations of IgG-mediated autoimmune diseases, including systemic lupus erythematosus (SLE). Preliminary data of the trial demonstrated a favorable safety and tolerability profile…