AMPEL BioSolutions Seeks $12.5M to Market its Personalized Blood Test for Lupus

AMPEL BioSolutions Seeks $12.5M to Market its Personalized Blood Test for Lupus
0
(0)

AMPEL BioSolutions is seeking $12.5 million in funding to market LuGene, a personalized blood test that uses genetic information from a patient to predict treatment response and lupus flares.

The company has initiated a Series A round of financing, which refers to the first significant step of venture capital financing.

LuGene initially targeted lupus, but the test may be utilized for other autoimmune or inflammatory diseases. AMPEL’s goal is to have LuGene available for regular use by physicians in the next few years. According to the company, LuGene could change the way chronic diseases are treated.

The lab test is ready for commercialization to support treatment decisions and help improve health care based on a patient’s genes. LuGene analyzes genetic results using machine learning to predict when flares are going to occur.

“Predicting lupus disease flares, allowing initiation or modification of disease-modifying therapies, should have an important impact on patient health,” Mary K. Crow, MD, physician-in-chief at the Hospital for Special Surgery, and chief of rheumatology at Weill Cornell Medical Center, said in a press release.

“LuGene seems to be an important step in that direction. Application of knowledge of molecular mechanisms to aid in patient management is the future of lupus care and will benefit patients and improve outcomes,” added Crow.

Studies with AMPEL’s gene-based approach showed that machine learning can help predict disease status in people with lupus.

“Unpredictable flares can be a daily battle for many patients with lupus and other autoimmune conditions,” said Deidre Baptista and Kirsten Maeda, the “GEE Twins for Lupus” and board members at the Lupus Foundation of Northern California. “From personal experience, we know flares come and go without warning and make it challenging for patients. AMPEL’s promising breakthrough of their LuGene diagnostic is the news patients have desperately been waiting to hear.”

“We applaud AMPEL BioSolutions’s goal to help identify patients’ disease activity in real time,” they added.

LuGene will also help companies pick the right patients for their clinical trials. Enrolling participants with the greatest likelihood of responding to a treatment candidate is important, as tests in people less likely to show benefits could end the clinical development of a medicine that may still be effective in a specific group of patients.

By helping to recruit suitable participants, AMPEL’s approach may maximize success of a clinical trial, the company said.

“Lupus care will greatly benefit from more precise evaluation of patients. LuGene seems to be an important step in that direction,” said Daniel J. Wallace, MD, a professor of medicine at the David Geffen School of Medicine at UCLA. “Patients would greatly benefit from a better way to relate their symptoms to immune abnormalities.”

Iqra holds a MSc in Cellular and Molecular Medicine from the University of Ottawa in Ottawa, Canada. She also holds a BSc in Life Sciences from Queen’s University in Kingston, Canada. Currently, she is completing a PhD in Laboratory Medicine and Pathobiology from the University of Toronto in Toronto, Canada. Her research has ranged from across various disease areas including Alzheimer’s disease, myelodysplastic syndrome, bleeding disorders and rare pediatric brain tumors.
Total Posts: 51
José is a science news writer with a PhD in Neuroscience from Universidade of Porto, in Portugal. He has also studied Biochemistry at Universidade do Porto and was a postdoctoral associate at Weill Cornell Medicine, in New York, and at The University of Western Ontario in London, Ontario, Canada. His work has ranged from the association of central cardiovascular and pain control to the neurobiological basis of hypertension, and the molecular pathways driving Alzheimer’s disease.
×
Iqra holds a MSc in Cellular and Molecular Medicine from the University of Ottawa in Ottawa, Canada. She also holds a BSc in Life Sciences from Queen’s University in Kingston, Canada. Currently, she is completing a PhD in Laboratory Medicine and Pathobiology from the University of Toronto in Toronto, Canada. Her research has ranged from across various disease areas including Alzheimer’s disease, myelodysplastic syndrome, bleeding disorders and rare pediatric brain tumors.
Latest Posts
  • LuGENE
  • BioMed X
  • Stelara new data
  • p40

How useful was this post?

Click on a star to rate it!

Average rating 0 / 5. Vote count: 0

No votes so far! Be the first to rate this post.

As you found this post useful...

Follow us on social media!

We are sorry that this post was not useful for you!

Let us improve this post!

Tell us how we can improve this post?