Author Archives: Ana Pamplona, PhD

Families of Lupus Patients Have Increased Prevalence of Autoantibodies, 12-year Study Shows

A recent 12-year follow-up study performed on first-degree relatives (FDRs) of patients with systemic lupus erythematosus (SLE) showed an increased frequency of autoantibodies such as anti-nuclear antibodies (ANA) when compared to healthy controls. The study, “Autoantibodies persist in relatives to systemic lupus erythematosus patients during 12 years follow-up,” was published…

Lupus Study Looks at Possibilities of Long-term Remission

A new and unusual study describes a three- to 32-year follow-up analysis of systemic lupus erythematosus (SLE) patients to understand the number who achieve complete remission (three years) and subsequently remain in remission. The study, titled “Analysis of Complete Remission in Lupus Patients over a period of 32 years,”…

Regulatory T Cell Deficient Mice Develop Lupus-Like Disease

A new study showed that mice deficient in regulatory T cells develop systemic autoimmune disease similar to lupus. The study entitled “Regulatory T cell deficient scurfy mice develop systemic autoimmune features resembling lupus-like disease” was published in Arthritis Research & Therapy. Scurfy mice do…